Pseudomonas /Pseu·do·mo·nas/ (-mo´nas) a genus of gram-negative, aerobic bacteria, some species of which are
pathogenic for plants and vertebrates. P. aerugino´sa produces the blue-green pigment pyocyanin, which gives the
color to "blue pus" and causes various human diseases; P. acido´vorans, P. alcali´genes, P. fluores´cens, P. picket´tii,
P. pseudoalcali´genes, P. pu´tida, P. putrefa´ciens, P. stut´zeri, and P. vesicula´ris are opportunistic pathogens.
http://medical-dictionary.thefreedictionary.com/PSEUDOMONAS

PSEUDOMONAS:  These bacteria are resistant to most antibiotics and they are capable of surviving in conditions that
few other organisms can tolerate. These pathogens colonize the lungs of cystic fibrosis patients, increasing the mortality
rate of individuals with the disease. Infection can occur at many sites and can lead to urinary tract infections, sepsis,
pneumonia, pharyngitis, and a lot of other problems. Pseudomonas aeruginosa;  pathogenicity involves several
toxins and chemicals which the bacterium secretes upon infection. The lipopolysaccharide layer helps the cell adhere to
host tissues and prevents leukocytes from ingesting and lysing the organism. Lipases and exotoxins then procede to
destroy host cell tissue which then leads to the complications associated with infection. Burkholderia (Pseudomonas)
cepacia is an opportunistic pathogen of cystic fibrosis patients. Stenotrophomonas maltophila (formerly known as
Xanthomonas maltophila) is very similar to the Pseudomonads. S. maltophila also harbors significant resistance to
many antibiotics considered effective for treating Pseudomonas infections












Pseudomonas putrefaciens, a strongly H2S-producing pseudomonad, was isolated from 10 human infections over a
two-year period. In one patient the organism was repeatedly isolated from a phlegmone developing in the depth of a
varicose leg ulcer. This is the first report on the occurrence of Ps. putrefaciens in humans outside the USA and the first
to provide the detailed account of a clinical observation where the opportunistic pathogenic role of this unfamiliar
organism has been sufficiently documented. Data are presented on the bacteriological properties and on the antibiotic
sensitivity of Ps. putrefaciens.
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=475921
Figure 9. (click image to zoom) By day 10,
overlying skin succumbed to induration,
gangrene, and necrosis. Infection continued
to progress, and patient expired. Reprinted
from Am J Med (1988;85:490-494), Copyright
© 1988, Excerpta Medica, Inc.[6

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